Chengchuan Wu

Improved Sodium Magnetic Resonance Imaging of the Brain

Project Summary:

Sodium Magnetic Resonance Imaging offers complementary information to traditional proton (hydrogen) MRI. The signal available for imaging sodium is however orders of magnitude smaller than its proton MRI counterpart, therefore providing technical challenges to acquire sufficiently high-resolution images in sufficiently constrained scan times. Both the Institute of Neuroscience and Medicine at FZJ and the Melbourne Brain Centre Imaging Unit at UoM have expertise in sodium MRI acquisition and analysis, and high-field MRI scanners equipped with the required hardware. This PhD project will explore the possibilities to improve the time efficiency or image quality of sodium MRI. The technique will be used to better understand the healthy brain, and to derive biomarkers for translational application to epilepsy and traumatic brain injury.

Project Duration: 2019-2022


Home University: The University of Melbourne

Partner University: RWTH Aachen University

Graduate Research Student Profile

Chengchuan is a PhD candidate of the biomedical engineering department. He recently completed a Master of Engineering at the University of Melbourne, and has a Bachelor of Biomedical Engineering degree from Sun Yat-sen University, China. His previous research focused on quantitative susceptibility mapping, which can be used to infer the iron distribution in the human brain. Over the past year, he explored ways to suppress image artifacts and improve the mapping result. He is interested in modelling, acquisition sequences and post-processing algorithms for sodium MRI.

Chengchuan finds Melbourne to be a food heaven with a great variety of cuisines from all around the world (Chinese, Greek, Italian, Korean… you name it). He enjoys travelling in the city and trying different restaurants to satisfy his hunger. He also loves the outdoor activities in Victoria including star-gazing by Lake Tyrell.